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The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats

The hypocretin receptor (HcrtR) antagonist almorexant (ALM) has potent hypnotic actions but little is known about neurocognitive performance in the presence of ALM. HcrtR antagonists are hypothesized to induce sleep by disfacilitation of wake-promoting systems whereas GABA(A) receptor modulators suc...

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書誌詳細
主要な著者: Morairty, Stephen R., Wilk, Alan J., Lincoln, Webster U., Neylan, Thomas C., Kilduff, Thomas S.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907703/
https://ncbi.nlm.nih.gov/pubmed/24550767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00003
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