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The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats

The hypocretin receptor (HcrtR) antagonist almorexant (ALM) has potent hypnotic actions but little is known about neurocognitive performance in the presence of ALM. HcrtR antagonists are hypothesized to induce sleep by disfacilitation of wake-promoting systems whereas GABA(A) receptor modulators suc...

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Detalhes bibliográficos
Main Authors: Morairty, Stephen R., Wilk, Alan J., Lincoln, Webster U., Neylan, Thomas C., Kilduff, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907703/
https://ncbi.nlm.nih.gov/pubmed/24550767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00003
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