Locus Coeruleus and Tuberomammillary Nuclei Ablations Attenuate Hypocretin/Orexin Antagonist-Mediated REM Sleep123

Hypocretin 1 and 2 (Hcrts; also known as orexin A and B), excitatory neuropeptides synthesized in cells located in the tuberal hypothalamus, play a central role in the control of arousal. Hcrt inputs to the locus coeruleus norepinephrine (LC NE) system and the posterior hypothalamic histaminergic tu...

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Bibliographic Details
Published in:eNeuro
Main Authors: Schwartz, Michael D., Nguyen, Alexander T., Warrier, Deepti R., Palmerston, Jeremiah B., Thomas, Alexia M., Morairty, Stephen R., Neylan, Thomas C., Kilduff, Thomas S.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2016
Subjects:
New Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801942/
https://ncbi.nlm.nih.gov/pubmed/27022631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0018-16.2016
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