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Orexin/hypocretin system modulates amygdala-dependent threat learning through the locus coeruleus

Survival in a dangerous environment requires learning about stimuli that predict harm. Although recent work has focused on the amygdala as the locus of aversive memory formation, the hypothalamus has long been implicated in emotional regulation, and the hypothalamic neuropeptide orexin (hypocretin)...

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Detalhes bibliográficos
Main Authors: Sears, Robert M., Fink, Ann E., Wigestrand, Mattis B., Farb, Claudia R., de Lecea, Luis, LeDoux, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864341/
https://ncbi.nlm.nih.gov/pubmed/24277819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320325110
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