The Dual Orexin/Hypocretin Receptor Antagonist, Almorexant, in the Ventral Tegmental Area Attenuates Ethanol Self-Administration

Recent studies have implicated the hypocretin/orexinergic system in reward-seeking behavior. Almorexant, a dual orexin/hypocretin R(1) and R(2) receptor antagonist, has proven effective in preclinical studies in promoting sleep in animal models and was in Phase III clinical trials for sleep disorder...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Srinivasan, Subhashini, Simms, Jeffrey A., Nielsen, Carsten K., Lieske, Steven P., Bito-Onon, Jade J., Yi, Henry, Hopf, Frederic Woodward, Bonci, Antonello, Bartlett, Selena E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448615/
https://ncbi.nlm.nih.gov/pubmed/23028593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044726
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