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Kinetic Analysis of Base Pairing Preference for Nucleotide Incorporation Opposite Template Pyrimidines by Human DNA Polymerase ι

DNA polymerase (pol) ι, a member of the mammalian Y-family of DNA polymerases involved in translesion DNA synthesis, has been previously suggested to peculiarly utilize Hoogsteen base pairing for DNA synthesis opposite template purines, unlike pols η and κ which utilize Watson-Crick base pairing. To...

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Autors principals: Choi, Jeong-Yun, Lim, Seonhee, Eoff, Robert L., Guengerich, F. Peter
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010588/
https://ncbi.nlm.nih.gov/pubmed/19376129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.023
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