Raisanberine protected pulmonary arterial rings and cardiac myocytes of rats against hypoxia injury by suppressing NADPH oxidase and calcium influx

AIM: To investigate the protection of pulmonary arterial rings and cardiac myocytes of rats by raisanberine (RS), a derivative of berberine, against hypoxia injury and to elucidate the action mechanisms. METHODS: Adult SD rats were exposed to intermittent hypoxia for 17 d or 28 d. The pulmonary arte...

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Main Authors: Gao, Jie, Tang, Yi-qun, Dai, De-zai, Cheng, Yu-si, Zhang, Guo-lin, Zhang, Can, Dai, Yin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010357/
https://ncbi.nlm.nih.gov/pubmed/22555370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.7
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