Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCε in the heart, which are mitigated by endothelin receptor antagonist CPU0213

AIM: Spatial dispersion of bioactive substances in the myocardium could serve as pathological basis for arrhythmogenesis and cardiac impairment by β-adrenoceptor stimulation. We hypothesized that dispersed NADPH oxidase, protein kinase Cε (PKCε), early response gene (ERG), and matrix metalloproteina...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Yu-si, Dai, De-zai, Dai, Yin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006683/
https://ncbi.nlm.nih.gov/pubmed/19597524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.104
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