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Exonucleolytic proofreading increases the accuracy of DNA synthesis by human lymphocyte DNA polymerase alpha-DNA primase.

DNA polymerase-primase complex, isolated with an apparently undegraded alpha-subunit, was immunoaffinity-purified to near homogeneity from the human lymphoblast line HSC93. The undegraded state of the alpha-subunit was monitored by Western-blot analysis of crude cellular extracts and all active frac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bialek, G, Nasheuer, H P, Goetz, H, Grosse, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC401030/
https://ncbi.nlm.nih.gov/pubmed/2527747
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