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Exonucleolytic proofreading increases the accuracy of DNA synthesis by human lymphocyte DNA polymerase alpha-DNA primase.

DNA polymerase-primase complex, isolated with an apparently undegraded alpha-subunit, was immunoaffinity-purified to near homogeneity from the human lymphoblast line HSC93. The undegraded state of the alpha-subunit was monitored by Western-blot analysis of crude cellular extracts and all active frac...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Bialek, G, Nasheuer, H P, Goetz, H, Grosse, F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1989
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2527747/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03578.x
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