MUT-14 and SMUT-1 DEAD box RNA helicases have overlapping roles in germline RNAi and endogenous siRNA formation

More than two thousand C. elegans genes are targeted for RNA silencing by the mutator complex, a specialized siRNA amplification module which is nucleated by the Q/N-rich protein MUT-16. The mutator complex localizes to Mutator foci adjacent to P granules at the nuclear periphery in germ cells [1]....

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Huvudupphovsmän: Phillips, Carolyn M., Montgomery, Brooke E., Breen, Peter C., Roovers, Elke F., Rim, Young-Soo, Ohsumi, Toshiro K., Newman, Martin A., van Wolfswinkel, Josien C., Ketting, Rene F., Ruvkun, Gary, Montgomery, Taiowa A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010136/
https://ncbi.nlm.nih.gov/pubmed/24684932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.02.060
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