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piRNAs and piRNA-dependent siRNAs protect conserved and essential C. elegans genes from misrouting into the RNAi pathway
piRNAs silence foreign genes, such as transposons, to preserve genome integrity, but also target endogenous mRNAs by mechanisms that are poorly understood. C. elegans piRNAs interact with both transposon and non-transposon mRNAs to initiate sustained silencing via the RNAi pathway. To assess the dys...
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| Publicat a: | Dev Cell |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550515/ https://ncbi.nlm.nih.gov/pubmed/26279487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.07.009 |
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