A tudor domain protein, SIMR-1, promotes siRNA production at piRNA-targeted mRNAs in C. elegans

piRNAs play a critical role in the regulation of transposons and other germline genes. In Caenorhabditis elegans, regulation of piRNA target genes is mediated by the mutator complex, which synthesizes high levels of siRNAs through the activity of an RNA-dependent RNA polymerase. However, the steps b...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Manage, Kevin I, Rogers, Alicia K, Wallis, Dylan C, Uebel, Celja J, Anderson, Dorian C, Nguyen, Dieu An H, Arca, Katerina, Brown, Kristen C, Cordeiro Rodrigues, Ricardo J, de Albuquerque, Bruno FM, Ketting, René F, Montgomery, Taiowa A, Phillips, Carolyn Marie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2020
Pynciau:
Chromosomes and Gene Expression
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255803/
https://ncbi.nlm.nih.gov/pubmed/32338603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56731
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