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MUT-16 promotes formation of perinuclear Mutator foci required for RNA silencing in the C. elegans germline

RNA silencing can be initiated by endogenous or exogenously delivered siRNAs. In Caenorhabditis elegans, RNA silencing guided by primary siRNAs is inefficient and therefore requires an siRNA amplification step involving RNA-dependent RNA polymerases (RdRPs). Many factors involved in RNA silencing lo...

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Hlavní autoři: Phillips, Carolyn M., Montgomery, Taiowa A., Breen, Peter C., Ruvkun, Gary
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403012/
https://ncbi.nlm.nih.gov/pubmed/22713602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.193904.112
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