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MUT-16 promotes formation of perinuclear Mutator foci required for RNA silencing in the C. elegans germline

RNA silencing can be initiated by endogenous or exogenously delivered siRNAs. In Caenorhabditis elegans, RNA silencing guided by primary siRNAs is inefficient and therefore requires an siRNA amplification step involving RNA-dependent RNA polymerases (RdRPs). Many factors involved in RNA silencing lo...

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Detalhes bibliográficos
Main Authors: Phillips, Carolyn M., Montgomery, Taiowa A., Breen, Peter C., Ruvkun, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403012/
https://ncbi.nlm.nih.gov/pubmed/22713602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.193904.112
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