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Paradigms of protein degradation by the proteasome
The proteasome is the main proteolytic machine in the cytosol and nucleus of eukaryotic cells where it degrades hundreds of regulatory proteins, removes damaged proteins, and produces peptides that are presented by MHC complexes. New structures of the proteasome particle show how its subunits are ar...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010099/ https://ncbi.nlm.nih.gov/pubmed/24632559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.02.002 |
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