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Defining the geometry of the two-component proteasome degron
The eukaryotic 26S proteasome controls cellular processes by degrading specific regulatory proteins. Most proteins are targeted for degradation by a signal or degron that consists of two parts: a proteasome-binding tag, typically covalently attached polyubiquitin chains, and an unstructured region t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129032/ https://ncbi.nlm.nih.gov/pubmed/21278740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.521 |
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