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Rad23 escapes degradation because it lacks a proteasome initiation region

Rad23 is an adaptor protein that binds to both ubiquitinated substrates and to the proteasome. Despite its association with the proteasome, Rad23 escapes degradation. Here we show that Rad23 remains stable because it lacks an effective initiation region where the proteasome can engage the protein an...

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Detalhes bibliográficos
Main Authors: Fishbain, Susan, Prakash, Sumit, Herrig, Annie, Elsasser, Suzanne, Matouschek, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069258/
https://ncbi.nlm.nih.gov/pubmed/21304521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1194
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