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Rad23 escapes degradation because it lacks a proteasome initiation region

Rad23 is an adaptor protein that binds to both ubiquitinated substrates and to the proteasome. Despite its association with the proteasome, Rad23 escapes degradation. Here we show that Rad23 remains stable because it lacks an effective initiation region where the proteasome can engage the protein an...

詳細記述

保存先:
書誌詳細
主要な著者: Fishbain, Susan, Prakash, Sumit, Herrig, Annie, Elsasser, Suzanne, Matouschek, Andreas
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069258/
https://ncbi.nlm.nih.gov/pubmed/21304521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1194
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