Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways

Is the order in which proteins assemble into complexes important for biological function? Here, we seek to address this by searching for evidence of evolutionary selection for ordered protein complex assembly. First, we experimentally characterize the assembly pathways of several heteromeric complex...

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Bibliographic Details
Main Authors: Marsh, Joseph A., Hernández, Helena, Hall, Zoe, Ahnert, Sebastian E., Perica, Tina, Robinson, Carol V., Teichmann, Sarah A.
Format: Artigo
Language:Inglês
Published: Cell Press 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009401/
https://ncbi.nlm.nih.gov/pubmed/23582331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.02.044
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