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Assembly reflects evolution of protein complexes

A homomer is formed by self-interacting copies of a protein unit. This is functionally important1,2, as in allostery3-5, and structurally crucial because mis-assembly of homomers is implicated in disease6,7. Homomers are widespread, with 50–70% of proteins with a known quaternary state assembling in...

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Bibliografiska uppgifter
Huvudupphovsmän: Levy, Emmanuel D., Erba, Elisabetta Boeri, Robinson, Carol V., Teichmann, Sarah A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658002/
https://ncbi.nlm.nih.gov/pubmed/18563089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06942
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