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Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways

Is the order in which proteins assemble into complexes important for biological function? Here, we seek to address this by searching for evidence of evolutionary selection for ordered protein complex assembly. First, we experimentally characterize the assembly pathways of several heteromeric complex...

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Detalles Bibliográficos
Main Authors: Marsh, Joseph A., Hernández, Helena, Hall, Zoe, Ahnert, Sebastian E., Perica, Tina, Robinson, Carol V., Teichmann, Sarah A.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009401/
https://ncbi.nlm.nih.gov/pubmed/23582331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.02.044
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