Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways

Is the order in which proteins assemble into complexes important for biological function? Here, we seek to address this by searching for evidence of evolutionary selection for ordered protein complex assembly. First, we experimentally characterize the assembly pathways of several heteromeric complex...

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Main Authors: Marsh, Joseph A., Hernández, Helena, Hall, Zoe, Ahnert, Sebastian E., Perica, Tina, Robinson, Carol V., Teichmann, Sarah A.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009401/
https://ncbi.nlm.nih.gov/pubmed/23582331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.02.044
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