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Acute reduction of oxygen tension enhances the induction of neurons from human fibroblasts

We and others have reported the successful conversion of human fibroblasts into functional induced neuronal (iN) cells; however the reprogramming efficiencies were very low. Robust reprogramming methods must be developed before iN cells can be used for translational applications such as disease mode...

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Main Authors: Davila, Jonathan, Chanda, Soham, Ang, Cheen Euong, Südhof, Thomas C., Wernig, Marius
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009399/
https://ncbi.nlm.nih.gov/pubmed/23562599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2013.03.020
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