N-myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross-regulation with c-myc.

To assess the impact of constitutive N-myc expression on lymphocytes, we generated lines of transgenic mice bearing the murine N-myc oncogene coupled to the immunoglobulin heavy chain enhancer (E mu). As in mice carrying an analogous c-myc construct, E mu-N-myc mice exhibit a limited overgrowth of c...

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Pubblicato in:	EMBO J
Autori principali:	Rosenbaum, H, Webb, E, Adams, J M, Cory, S, Harris, A W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400871/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2785918/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03435.x
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