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N-myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross-regulation with c-myc.

To assess the impact of constitutive N-myc expression on lymphocytes, we generated lines of transgenic mice bearing the murine N-myc oncogene coupled to the immunoglobulin heavy chain enhancer (E mu). As in mice carrying an analogous c-myc construct, E mu-N-myc mice exhibit a limited overgrowth of c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rosenbaum, H, Webb, E, Adams, J M, Cory, S, Harris, A W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1989
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC400871/
https://ncbi.nlm.nih.gov/pubmed/2785918
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