Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins.

Consistent with an ordered immunoglobulin (Ig) gene assembly process during precursor (pre-) B cell differentiation, we find that most Abelson murine leukemia virus (A-MuLV)-transformed pre-B cells derived from scid (severe combined immune deficient) mice actively form aberrant rearrangements of the...

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Pubblicato in:	EMBO J
Autori principali:	Blackwell, T K, Malynn, B A, Pollock, R R, Ferrier, P, Covey, L R, Fulop, G M, Phillips, R A, Yancopoulos, G D, Alt, F W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2785917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03433.x
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