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Comparison of different rearranged immunoglobulin kappa genes of a myeloma by electronmicroscopy and restriction mapping of cloned DNA: implications for "allelic exclusion".

We have studied the organization and function of different rearranged kappa genes in a myeloma, MOPC-21. Two kappa genes were cloned into Charon 4A and compared with each other and with a cloned germline CK gene by restriction mapping and electron microscopy. One MOPC-21 clone corresponds to the gen...

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Autori principali: Walfield, A M, Storb, U, Selsing, E, Zentgraf, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1980
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC324380/
https://ncbi.nlm.nih.gov/pubmed/6255429
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