Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins.

Consistent with an ordered immunoglobulin (Ig) gene assembly process during precursor (pre-) B cell differentiation, we find that most Abelson murine leukemia virus (A-MuLV)-transformed pre-B cells derived from scid (severe combined immune deficient) mice actively form aberrant rearrangements of the...

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Detalhes bibliográficos
Main Authors: Blackwell, T K, Malynn, B A, Pollock, R R, Ferrier, P, Covey, L R, Fulop, G M, Phillips, R A, Yancopoulos, G D, Alt, F W
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400869/
https://ncbi.nlm.nih.gov/pubmed/2785917
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