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Preferential rearrangement of the immunoglobulin kappa chain joining region J kappa 1 and J kappa 2 segments in mouse spleen DNA.

The V kappa-KpnI family, which constitutes approximately equal to 36% of mouse kappa chain variable region gene (V kappa) segments, conserves the Kpn I site (G-G-T-A-C-C) at the position corresponding to residues 35-37. Using this cleavage site, we were able to assess the relative recombination freq...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Nishi, M, Kataoka, T, Honjo, T
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1985
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390723/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3931074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6399
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