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Human kallistatin administration reduces organ injury and improves survival in a mouse model of polymicrobial sepsis
Kallistatin, a plasma protein, has been shown to exert multi-factorial functions including inhibition of inflammation, oxidative stress and apoptosis in animal models and cultured cells. Kallistatin levels are reduced in patients with sepsis and in lipopolysaccharide (LPS)-induced septic mice. Moreo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley & Sons Ltd
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4008229/ https://ncbi.nlm.nih.gov/pubmed/24467264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12242 |
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