Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis

INTRODUCTION: Kallistatin levels in the circulation are reduced in patients with sepsis and liver disease. Transgenic mice expressing kallistatin are resistant to lipopolysaccharide (LPS)-induced mortality. Here, we investigated the effect of kallistatin on survival and organ damage in mouse models...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Crit Care
Prif Awduron: Li, Pengfei, Guo, Youming, Bledsoe, Grant, Yang, Zhi-Rong, Fan, Hongkuan, Chao, Lee, Chao, Julie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445990/
https://ncbi.nlm.nih.gov/pubmed/25930108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0919-4
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