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Kallistatin inhibits TGF-β-induced endothelial–mesenchymal transition by differential regulation of microRNA-21 and eNOS expression

Kallistatin, an endogenous protein, consists of two structural elements: active site and heparin-binding domain. Kallistatin exerts beneficial effects on fibrosis by suppressing transforming growth factor (TGF)-β synthesis in animal models. TGF-β is the most potent inducer of endothelial–mesenchymal...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Guo, Youming, Li, Pengfei, Bledsoe, Grant, Yang, Zhi-Rong, Chao, Lee, Chao, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560618/
https://ncbi.nlm.nih.gov/pubmed/26156753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2015.06.021
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