Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis

INTRODUCTION: Kallistatin levels in the circulation are reduced in patients with sepsis and liver disease. Transgenic mice expressing kallistatin are resistant to lipopolysaccharide (LPS)-induced mortality. Here, we investigated the effect of kallistatin on survival and organ damage in mouse models...

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Библиографические подробности
Опубликовано в: :Crit Care
Главные авторы: Li, Pengfei, Guo, Youming, Bledsoe, Grant, Yang, Zhi-Rong, Fan, Hongkuan, Chao, Lee, Chao, Julie
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445990/
https://ncbi.nlm.nih.gov/pubmed/25930108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0919-4
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