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Depletion of endogenous kallistatin exacerbates renal and cardiovascular oxidative stress, inflammation, and organ remodeling

Kallistatin (KS) levels are reduced in the kidney and blood vessels under oxidative stress conditions. To determine the function of endogenous KS in the renal and cardiovascular systems, KS levels were depleted by daily injection of anti-rat KS antibody into DOCA-salt hypertensive rats for 10 days....

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Detalhes bibliográficos
Main Authors: Liu, Yuying, Bledsoe, Grant, Hagiwara, Makato, Shen, Bo, Chao, Lee, Chao, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469672/
https://ncbi.nlm.nih.gov/pubmed/22811485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00257.2012
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