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Blockade of endogenous tissue kallikrein aggravates renal injury by enhancing oxidative stress and inhibiting matrix degradation

Levels of tissue kallikrein (TK) are significantly lower in the urine of patients with kidney failure, and TK expression is specifically diminished in rat kidney after recovery from ischemia-reperfusion injury. In this study, we investigated the functional consequence of blocking endogenous TK activ...

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Detalhes bibliográficos
Main Authors: Liu, Yuying, Bledsoe, Grant, Hagiwara, Makato, Yang, Zhi-Rong, Shen, Bo, Chao, Lee, Chao, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853308/
https://ncbi.nlm.nih.gov/pubmed/20089675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00518.2009
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