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Labeled Ligand Displacement: Extending NMR-Based Screening of Protein Targets
[Image: see text] NMR spectroscopy has enjoyed widespread success as a method for screening protein targets, especially in the area of fragment-based drug discovery. However, current methods for NMR-based screening all suffer certain limitations. Two-dimensional methods like “SAR by NMR” require iso...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007843/ https://ncbi.nlm.nih.gov/pubmed/24900211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1000849 |
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