Labeled Ligand Displacement: Extending NMR-Based Screening of Protein Targets

[Image: see text] NMR spectroscopy has enjoyed widespread success as a method for screening protein targets, especially in the area of fragment-based drug discovery. However, current methods for NMR-based screening all suffer certain limitations. Two-dimensional methods like “SAR by NMR” require iso...

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Detaylı Bibliyografya
Asıl Yazarlar: Swann, Steven L., Song, Danying, Sun, Chaohong, Hajduk, Philip J., Petros, Andrew M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2010
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007843/
https://ncbi.nlm.nih.gov/pubmed/24900211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1000849
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