Učitavanje...
Discovery of Ligands for a Novel Target, the Human Telomerase RNA, Based on Flexible-Target Virtual Screening and NMR
The human ribonucleoprotein telomerase is a validated anticancer drug target, and hTRP2b is a part of the human telomerase RNA (hTR) essential for its activity. Interesting ligands that bind hTR-P2b were identified by iteratively using a tandem structure-based approach: docking of potential ligands...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651004/ https://ncbi.nlm.nih.gov/pubmed/18950148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800825n |
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