Chargement en cours...
Virtual Ligand Screening Combined with NMR to identify Dvl PDZ domain inhibitors targeting the Wnt signaling
Virtual ligand screening (VLS) is a powerful technique to identify potential hits of targets and to increase hit rates. Here, we describe how we used this technique combined with NMR (15)N HSQC experiments to obtain small molecules that bind to the PDZ domain of Dvl targeting the Wnt signaling pathw...
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3964848/ https://ncbi.nlm.nih.gov/pubmed/22956130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-008-3_2 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|