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Exploring Target-Selectivity Patterns of Molecular Scaffolds

[Image: see text] We investigate the question of whether target-selective molecular scaffolds can be identified on the basis of currently available compound activity data. Starting from a pool of 17745 public domain compounds with activity annotations for 433 human targets, we ultimately identify, t...

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Autores principales: Hu, Ye, Bajorath, Jürgen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2010
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007699/
https://ncbi.nlm.nih.gov/pubmed/24900176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml900024v
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