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Donor hematopoiesis in mice following total lymphoid irradiation requires host T-regulatory cells for durable engraftment

Total lymphoid irradiation (TLI) with antithymocyte globulin (ATG) is a unique regimen that prepares recipients for allogeneic hematopoietic cell transplantation by targeting lymph nodes, while sparing large areas of the bone marrow. TLI is reported to increase the frequency of CD4(+)CD25(+)FoxP3(+)...

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Main Authors: Müller, Antonia M. S., Poyser, Jessica, Küpper, Natascha J., Burnett, Cassandra, Ko, Rose M., Kohrt, Holbrook E.K., Florek, Mareike, Zhang, Pei, Negrin, Robert S., Shizuru, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007614/
https://ncbi.nlm.nih.gov/pubmed/24591203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-530212
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