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Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning

T cells are widely used to promote engraftment of hematopoietic stem cells (HSCs) during an allogeneic hematopoietic cell transplantation. Their role in overcoming barriers to HSC engraftment is thought to be particularly critical when patients receive reduced doses of preparative chemotherapy and/o...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Müller, Antonia M. S., Florek, Mareike, Kohrt, Holbrook E. K., Küpper, Natascha J., Filatenkov, Alexander, Linderman, Jessica A., Hadeiba, Husein, Negrin, Robert S., Shizuru, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096509/
https://ncbi.nlm.nih.gov/pubmed/27815446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500715
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