Donor hematopoiesis in mice following total lymphoid irradiation requires host T-regulatory cells for durable engraftment

Total lymphoid irradiation (TLI) with antithymocyte globulin (ATG) is a unique regimen that prepares recipients for allogeneic hematopoietic cell transplantation by targeting lymph nodes, while sparing large areas of the bone marrow. TLI is reported to increase the frequency of CD4(+)CD25(+)FoxP3(+)...

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Bibliografiska uppgifter
Huvudupphovsmän: Müller, Antonia M. S., Poyser, Jessica, Küpper, Natascha J., Burnett, Cassandra, Ko, Rose M., Kohrt, Holbrook E.K., Florek, Mareike, Zhang, Pei, Negrin, Robert S., Shizuru, Judith A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2014
Ämnen:
Transplantation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007614/
https://ncbi.nlm.nih.gov/pubmed/24591203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-530212
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