Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas

BACKGROUND: Kinase module of Mediator complex (‘CDK8 submodule') consists of four subunits: CDK8, Cyclin C, MED12, and MED13. Recently, we reported recurrent MED12 mutations in 70% of uterine leiomyomas. The aim of this study was to analyse whether mutations in other components of the module co...

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Detalhes bibliográficos
Main Authors: Mäkinen, N, Heinonen, H-R, Sjöberg, J, Taipale, J, Vahteristo, P, Aaltonen, L A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007231/
https://ncbi.nlm.nih.gov/pubmed/24642626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.138
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