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Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas
BACKGROUND: Kinase module of Mediator complex (‘CDK8 submodule') consists of four subunits: CDK8, Cyclin C, MED12, and MED13. Recently, we reported recurrent MED12 mutations in 70% of uterine leiomyomas. The aim of this study was to analyse whether mutations in other components of the module co...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007231/ https://ncbi.nlm.nih.gov/pubmed/24642626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.138 |
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