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Single Nucleotide Variants in Transcription Factors Associate More Tightly with Phenotype than with Gene Expression

Mapping the polymorphisms responsible for variation in gene expression, known as Expression Quantitative Trait Loci (eQTL), is a common strategy for investigating the molecular basis of disease. Despite numerous eQTL studies, the relationship between the explanatory power of variants on gene express...

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Autori principali: Sudarsanam, Priya, Cohen, Barak A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006743/
https://ncbi.nlm.nih.gov/pubmed/24784239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004325
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