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Single Nucleotide Variants in Transcription Factors Associate More Tightly with Phenotype than with Gene Expression

Mapping the polymorphisms responsible for variation in gene expression, known as Expression Quantitative Trait Loci (eQTL), is a common strategy for investigating the molecular basis of disease. Despite numerous eQTL studies, the relationship between the explanatory power of variants on gene express...

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Autors principals: Sudarsanam, Priya, Cohen, Barak A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006743/
https://ncbi.nlm.nih.gov/pubmed/24784239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004325
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