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Drosha Promotes Splicing of a Pre-microRNA-like Alternative Exon

The ribonuclease III enzyme Drosha has a central role in the biogenesis of microRNA (miRNA) by binding and cleaving hairpin structures in primary RNA transcripts into precursor miRNAs (pre-miRNAs). Many miRNA genes are located within protein-coding host genes and cleaved by Drosha in a manner that i...

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Detalhes bibliográficos
Main Authors: Havens, Mallory A., Reich, Ashley A., Hastings, Michelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006729/
https://ncbi.nlm.nih.gov/pubmed/24786770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004312
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