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Drosha Promotes Splicing of a Pre-microRNA-like Alternative Exon
The ribonuclease III enzyme Drosha has a central role in the biogenesis of microRNA (miRNA) by binding and cleaving hairpin structures in primary RNA transcripts into precursor miRNAs (pre-miRNAs). Many miRNA genes are located within protein-coding host genes and cleaved by Drosha in a manner that i...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006729/ https://ncbi.nlm.nih.gov/pubmed/24786770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004312 |
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