In vitro functional characterization of 37 CYP2C9 allelic isoforms found in Chinese Han population

AIM: Cytochrome P450 2C9 (CYP2C9) is a polymorphic enzyme that is responsible for the metabolism of approximately 15% of clinically important drugs. The aim of this study was to assess the catalytic characteristics of 37 CYP2C9 allelic isoforms found in Chinese Han population on the metabolism of to...

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Bibliographische Detailangaben
Hauptverfasser: Dai, Da-peng, Wang, Yu-han, Wang, Shuang-hu, Geng, Pei-wu, Hu, Li-ming, Hu, Guo-xin, Cai, Jian-ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006465/
https://ncbi.nlm.nih.gov/pubmed/24077631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.123
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