Functional characterization of the defective CYP2C9 variant CYP2C9*18

Cytochrome P450 2C9 (CYP2C9) is one of the most important drugs metabolizing enzymes and accounts for the metabolism of about 13%–17% of clinical drugs. Like other members in CYP2 family, CYP2C9 gene exhibits great genetic polymorphism among different races and individuals. CYP2C9*18 is one CYP2C9 a...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Liu, Jian, Chen, Hao, Wang, Shuang‐Hu, Zhou, Quan, Geng, Pei‐Wu, Zhou, Yun‐Fang, Wu, Hua‐Lan, Shi, Hai‐Feng, Wang, Fang, Yang, Jie‐Fu, Cai, Jian‐Ping, Dai, Da‐Peng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842875/
https://ncbi.nlm.nih.gov/pubmed/33508175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.718
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