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In vitro functional characterization of 37 CYP2C9 allelic isoforms found in Chinese Han population
AIM: Cytochrome P450 2C9 (CYP2C9) is a polymorphic enzyme that is responsible for the metabolism of approximately 15% of clinically important drugs. The aim of this study was to assess the catalytic characteristics of 37 CYP2C9 allelic isoforms found in Chinese Han population on the metabolism of to...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006465/ https://ncbi.nlm.nih.gov/pubmed/24077631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.123 |
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