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Massive parallel-sequencing-based hydroxyl radical probing of RNA accessibility
Hydroxyl Radical Footprinting (HRF) is a tried-and-tested method for analysis of the tertiary structure of RNA and for identification of protein footprints on RNA. The hydroxyl radical reaction breaks accessible parts of the RNA backbone, thereby allowing ribose accessibility to be determined by det...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005689/ https://ncbi.nlm.nih.gov/pubmed/24569351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku167 |
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