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Massive parallel-sequencing-based hydroxyl radical probing of RNA accessibility

Hydroxyl Radical Footprinting (HRF) is a tried-and-tested method for analysis of the tertiary structure of RNA and for identification of protein footprints on RNA. The hydroxyl radical reaction breaks accessible parts of the RNA backbone, thereby allowing ribose accessibility to be determined by det...

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Bibliografski detalji
Glavni autori: Kielpinski, Lukasz Jan, Vinther, Jeppe
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005689/
https://ncbi.nlm.nih.gov/pubmed/24569351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku167
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