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Tissue specific CTCF occupancy and boundary function at the human growth hormone locus

The robust and tissue-specific activation of the human growth hormone (hGH) gene cluster in the pituitary and placenta constitutes an informative model for analysis of gene regulation. The five-gene hGH cluster is regulated by two partially overlapping sets of DNase I hypersensitive sites (HSs) that...

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Detalhes bibliográficos
Main Authors: Tsai, Yu-Cheng, Cooke, Nancy E., Liebhaber, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005687/
https://ncbi.nlm.nih.gov/pubmed/24561805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku139
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